Shafaqna English- Scientists have discovered that brain cells can use fat as a direct source of energy, overturning the long-standing belief that they run solely on sugar.
This process is managed by a key protein called DDHD2. When this protein malfunctions, it leads to energy failure in neurons and can cause serious neurological diseases.
In a landmark finding, researchers were able to reverse this damage in the lab. By feeding affected neurons specific fatty acids, they restored the cells’ energy production and normal function within just 48 hours. This offers a potential therapeutic strategy for conditions like Hereditary Spastic Paraplegia.
The discovery, hailed as a “game-changer,” could pave the way for new treatments for a range of currently incurable brain disorders by targeting the brain’s unique energy metabolism.
Source: University of Helsinki