Ziprasidone — Antipsychotic Drug By Pfizer Could Cause Life-Threatening Skin Condition

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SHAFAQNA – Patients and doctors will be clued-up by the utilization of a new brand added to the Geodon drug that 6 cases of ‘medication reaction with Eosinophilia and systemic indications’ (DRESS) have been reported all over the globe by individuals who utilized Ziprasidone. The FDA said that DRESS was a reason for deaths of individuals; nonetheless, none of the cases reported were fatal, however, death rates caused by DRESS can be of up to 10%.

In most of the patients, DRESS starts with the development of rashes on the body, and not long after that happens, it causes irritation of the lymph nodes and of the internal organs including lungs, pancreas, kidneys, liver and heart. The condition is likewise known to deliver high counts of Eosinophil the blood as the name of the condition proposes. Any of the following four: Eosinophilia, Lymphadenopathy, fever, skin reaction and one or more than one systemic complexities, for example, Nephritis, Myocarditis, Pancreatitis, Pericarditis, Pneumonitis and Hepatitis are the major features that demonstrate the existence of the serious condition.are the main attribute that show the presence of the severe condition.

Ziprasidone was included in the six cases reported as the severe condition emulated in a couple of weeks after beginning treatment with the medicine. In a couple of cases, withdrawal of the drug prompted the reoccurrence of the manifestations. In three of the cases, no other medications were accounted for to have been utilized along with Ziprasidone.

The US Food & Drug Administration said that if clinicians accept that medication reaction with Eosinophilia and systemic side effects is happening; the health care experts should instantly stop the treatment with Ziprasidone.

There is no known treatment for DRESS, said the FDA. The methods for dealing with the condition is by identifying it at an opportune time and ceasing the destructive drug. In case of extensive organ inclusion, the treatment with systemic Corticosteroids may be considered, as declared by the United States Food and Drug Administration.

Ziprasidone is an antipsychotic medication presently being utilized to reduce hallucinations, insanity, obsession and other psychotic manifestations in bipolar disorder and Schizophrenia.

Source : http://www.frontlinedesk.com/

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